Intermediate shuffled vector for each column of the permuted Operation PermuteY which eliminates the need to create an The implentation of fphi p value estimation, working since 8.0.6, Result of this and other changes "fphi -p" is now 25 times fasterĢ. In C++ intensive mathmatrix operations based on Eigen as a Polygenic runs 1.73 times faster compared Speed improvements in all SOLAR operations thanks to improvedĬompiler optimization. We recommend downloading the source code from github and compiling it on site.ġ. Some of the functionality may not work on individual macs. Mac version supports Intell machines only for now. We are debugging the issue but this may take some time as the old fortran optimization code will need to be rewritten in Intell math libraries. The polygenetic analyses such as genetic correlation still crush in the UKBB sized dataset. The GPU version of FPHI can do voxelwise heritability analyses in UKBB imaging data in under 6 hours on a Tesla P100 accelerator card on our server. The video tutorial on how to set up empirical heritability analyses in UKBB and HCP is forthcoming shortly. The heritability values can now be derived using the pedigree composed of the UKBB empirical kinship coefficient. This version has been vetted with univariate genetic analyses in UKBB. Corresponding video tutorials are available on our Education page. SOLAR-Eclipse now offers tutorials on single trait and pedigree as well as voxel-wise heritability analyses on UK BioBank imaging and genetics data.
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